Image
Home » IHC Antibodies » MSH 2 (25D12)

MSH 2 (25D12)

MSH 2 (25D12)

MSH2 is a mismatch repair gene commonly associated with Hereditary Non-Polyposis Colorectal Cancer (HNPCC). This gene was identified as a locus frequently mutated in HNPCC. When cloned, it is a human homolog of the E. coli DNA mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC.
 
STAINING PATTERN : Nuclear
POSITIVE CONTROL : Tonsil or colon carcinoma
CLONE : 25D12
VOLUME :
PL1498-R7            7 ML RTU 70 TEST
PL1498-R1            1 ML RTU 10 TEST
PL1498-1               1 ML 1/200 2000 TEST
PL1498-0,1         0,1 ML 1/200 200 TEST