Home » IHC Antibodies » DOG 1 (1.1)

DOG 1 (1.1)

İncele

DOG 1 (1.1)

Dog1 is a cell surface protein of unknown function selectively expressed in gastrointestinal stromal tumors (GIST). Among GIST cases with KIT mutations the Dog1 antibody identified 11% more cases than c-Kit antibody . Dog1 identifies vast majority of both c-Kit negative and PDGFRA mutated GIST cases that may still benefit from imatinib mesylate (Gleevac), an inhibitor of the kit tyrosin kinase.

STAINING PATTERN : Cytoplasmic , Membranous

POSITIVE CONTROL : Gastrointestinal Stromal Tumors

CLONE : 1.1

VOLUME :

PL1933-R7 7 ML RTU 70 TEST

PL1933-R1 1 ML RTU 10 TEST

PL1933-1 1 ML 1/200 2000 TEST

PL1933-0,1 0,1 ML 1/200 200 TEST

DATASHEET