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PMS2 (EP51)

PMS2 (EP51)

PMS2 is a gene that encodes for DNA repair proteins involved in mismatch repair. Carriers of the mismatch repair gene mutations have a high lifetime risk of developing Hereditary Non-Polyposis Colon Cancer (HNPCC) and several other cancers including endometrial cancer due to microsatellite instability (MSI) caused by accumulation of DNA replication errors in proliferating cells.
 
STAINING PATTERN : Nuclear
POSITIVE CONTROL : Breast, Skin, Cervix, Tonsil, Transitional Cell Carcinoma, Colon Carcinoma
CLONE : EP51
VOLUME :
PL2120-R7          7 ML RTU 70 TEST
PL2120-R1          1 ML RTU 10 TEST
PL2120-1             1 ML 1/100 1000 TEST
PL2120-0,1       0,1 ML 1/100 100 TEST